Nov 12, 2015 viral hepatitis b and c virus hbv and hcv are responsible for the most of chronic liver disease worldwide and are transmitted by parenteral route, sexual and vertical transmission. The most common types of viral hepatitis are a, b, and c. Statistics estimated 6,700 new infections in 2017 estimated 22,200 new infections in 2017. Worldwide, at least 11 genetically distinct genotypes and all products derived from human blood are prepared exclusively from the blood multiple subtypes and virus variants have been described. The genotype of the virus is the primary determinant of the rate of response to this treatment regimen, with genotype 1 being the most resistant. Viral hepatitis an introduction hepatitis, or inflammation of the liver, can be caused by several very different viruses. Jun 12, 2017 hepatitis, a general term referring to inflammation of the liver, may result from various causes, both infectious ie, viral, bacterial, fungal, and parasitic organisms and noninfectious eg, alcohol, drugs, autoimmune diseases, and metabolic diseases. While all three types of hepatitis can cause similar symptoms, each virus is spread in different ways. Viral hepatitis is primarily diagnosed through blood tests for levels of viral antigens such as the hepatitis b surface or core antigen, anti viral antibodies such as the antihepatitis b surface antibody or antihepatitis a antibody, or viral dnarna. The manual is intended for use by physicians, nurses. Since the last consensus conference on the management of chronic viral hepatitis, a number of studies looking at modifications of the standard course of. Symptoms of all types of viral hepatitis are similar and can include one or more of the following.
Who estimates that hepatitis e caused approximately 44 000 deaths in 2015 accounting for 3. Symptoms of hepatitis are universal, regardless if caused by an infectious agent or chronic condition, and can include fatigue, anorexia, abdominal pain, fever, diarrhea, vomiting, jaundice. Arteritis viral free download as powerpoint presentation. The abcs of hepatitis for health professionals hepatitis a. Aplastic anemia is a recognized complication of viral hepatitis, but, to our knowledge, no cases associated with type b hepatitis have been described. The acute form of hepatitis, generally caused by viral infection, is characterized by constitutional symptoms that are typically selflimiting. Hepatitis has a broad spectrum of presentations that range from a complete lack of symptoms to severe liver failure. Hepatitis c virus hcv is a positivestrand rna virus belonging to the hepacivirus genus in the family flaviviridae. Chronic hepatitis presents similarly, but can manifest signs and symptoms specific to liver dysfunction with long. As with so many diseases, weve come a long way in understanding viral hepatitis, notably two chronic and serious forms. Ambas as vacinas sao administradas por via intramuscular e podem ser dadas a adultos e a criancas estas tomam metade da dose do adulto. Autoimmune hepatitis may cause other symptoms that involve other body systems. Pdf viral hepatitis represents a disease entity caused by at least five unrelated viruses whose primary tissue tropism is the hepatocyte. Hav virus da hepatite a do ingles hepatitis a virus hbcag antigeno core do.
Hepatitis c is the most common chronic bloodborne infection in the united states. Acute hepatitis, s d ryder and i j beckingham, bmj 2001. The guidance provided in this manual is based on current recommendations of the centers for disease control and prevention cdcs advisory committee for immunization practices acip. Hepatite ede decorrencia rara no brasil, e comum na africa e asia, euma doenca infecciosa viral, sua transmissao e fecaoral. The hev genome comprises a nonsegmented positivesense rna chain and the virus is nonenveloped acha and szyfres, 2003. Eav, an rna virus classified in the genus, arterivirus, family. Liver biopsy specimen from a hepatitis c virus infected patient shows very prominent deposits of hcvag, with a distinct granular pattern in the hepatocyte located in the center of the field. Viral hepatitis can be due to one of at least five different viruses, designated hepatitis a, b, c, and e. Equine viral arteritis eva is a contagious viral disease of equids caused by equine arteritis virus. O hcv e o principal agente etiologico da hepatite cronica anteriormente denominada hepatite naoa naob. Hepatitis prevention program florida department of health.
The mission and vision of the hepatitis prevention program is to prevent the transmission of viral hepatitis and eliminate viral hepatitis in florida. Visao geral da hepatite viral aguda disturbios hepaticos e. Most people have no symptoms, but some have vague symptoms, such as a general feeling of illness, poor appetite, and. The past few decades have brought remarkable victories in relation to the prevention and control of viral hepatitis. Symptoms can include cessation of menstrual periods, joint pain and swelling, loss of appetite, and nausea. It helps your body digest food, store energy, and remove poisons. Several drugs are now on the market to manage hepatitis b, and a growing number of agents are available to cure hepatitis c in more than 90 percent of people. Though the reasons for this time relationship are not well known, it is theorized that the relative. Manual da hepatite b cronica readdownload original articles. Hepatites virais biblioteca virtual em saude ministerio da saude. Aplastic anemia associated with type b viral hepatitis.
Mar 19, 2020 the most common types of viral hepatitis are a, b, and c. A hepatite viral aguda e uma doenca comum em todo o mundo e tem diferentes causas. Most cases are caused by hepatitis a virus hav, hepatitis b. Hepatitis e is a liver disease caused by infection with a virus known as hepatitis e virus hev. Specifically, the ghss aims to achieve reductions in viral hepatitis related mortality 10% reduction by 2020 and 65%. Nys perinatal hepatitis b prevention program manual 2.
We report the case of a patient who developed severe aplastic anemia very early in the course of infection with hepatitis b virus. Hepatitis b vaccination in adolescents living in campinas, sao paulo, brazil aprova o protocolo clinico e diretrizes terapeuticas hepatite viral cronica b e coinfeccoes. Overview of chronic hepatitis msd manual consumer version. Visao geral da hepatite viral aguda disturbios hepaticos. Hepatitis c virus antigen hcvag in cytoplasm of hepatocytes, identified by fluorescein isothiocyanate labeled polyclonal igg antihcvag. Health assembly wha approved a global health sector strategy ghss on viral hepatitis, which calls for the elimination of hepatitis c virus hcv as a public health threat by 2030 2. Chronic hepatitis is inflammation of the liver that lasts at least 6 months. Are gay and bisexual men at risk for viral hepatitis. Marcadores serologicos en hepatitis viral e interpretacion dr. Hepatitis b spreads by contact with an infected persons blood, semen, or other body fluid. Perinatal hepb program manual new york state department of. Aplastic anemia associated with type b viral hepatitis jama.
Common causes include hepatitis b and c viruses and certain drugs. One important measure to reduce the burden of these infections is the diagnosis of acute and chronic cases of hbv and hcv. Laboratory diagnostics for hepatitis c virus infection. Perinatal hepb program manual new york state department. In the united states, the most common types of viral hepatitis are hepatitis a, hepatitis b, and hepatitis c. The virus originated from the stool of a volunteer orally infected with faeces from suspect cases of nona and nonb hepatitis balayan et al. Diagnostic and statistical manual of mental health. Hepatitis is an inflammation of the liver resulting from viruses, drugs, toxins, and other etiologies.
Hepatite nonvirale, hepatite medicamenteuse et hepatite. Abc of diseases of liver, pancreas, and biliary system. Dec 02, 2019 arteritis viral free download as powerpoint presentation. Viral hepatitis is an infection of the liver caused by. Hbs aghbe achbc igm phase aigu contage dna viral phase. Interferon lamivudina adefovir entecavir tenofovir tratamento indicacoes. They all affect the liver and have similar symptoms, but transmission and treatments differ. Hepatitis panelacute hepatitis panel quest diagnostics. Serological and molecular assays are used to identify acute and chronic cases of infection. In the united states, case reports of viral hepatitis are classified as hepatitis a, acute. Reliable methods for diagnosing hepatitis b virus hbv and hepatitis c virus hcv infection are essential to reduce the burden of these infections. Hepatitis b is caused by infection with the hepatitis b virus hbv, a partially. Hcv viral levels can be reduced to undetectable levels by a combination of interferon and the antiviral drug ribavirin. In this article, the current knowledge about hbv and hcv diagnosis is updated and emphased the characteristics.
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